BETOLVEX®
Cyanocobalamin
Dispensing forms :
Betolvex” injection: I ml (one ampoule) contains cyanocobalamin/tannin complex equivalent
to I mg cyanocobalamin
20 mg aluminium monostearate
sesame oil to make I ml.
Betolvex” tablets: Each tablet contains I mg cyanocobalamin.
Pharmocology :
Vitamin B” is essential for life and deficiency brings about the fatal disease of megaloblastic anaemia and/or neurological symptoms. Moreover, vitamin B” acts as a coenzyme in many im- portant enzymatic processes.
BETOLVEX® INJECTION :
Belolye,,”, injection is a vitamin B,,-tannin complex suspended in a sesame oil-aluminium monostearate gel. Vitamin B” is gradually released from the site of injection over a long period, simultaneously replenishing the stores in the liver. It is well established that injections of aqueous solutions of vitamin B” bring about a short-lasting rise m the serum level, without providing surplus vitamin B” for replenishing body stores. As the treatment of a deficiency disease can only be considered satisfactory when the patient’s physiological condition becomes completely normal, the Dumex research laboratories have de-
veloped a vitamin B” preparation with prolonged action.
Indications :
In the prophylaxis and therapy of pernicious anaemia and other conditions with vitamin B” de- ficiency.
Examples of such conditions are:
Total gastrectomy. which is always accompanied by hypovitaminosis.
Vitamin B” hypovitaminosis with macrocytic anaemia and/or neuropathy.
– after gastric resection
– after ileocoecal resection and proctocolectomy
– in sprue and symptomatic steatorrhoea
– in sur e afte intestinal shunt for adipositas
– with inadequate nutrition. where the cause is malnutrition or unsuitable diet, particularly in the case of elderly people who often suffer from atrophic gastritis, and vegetarians whose diet is entirely lacking in animal protein.
Contra-Indications :
Known allergy to vitamin B”. Leber’s optic atrophy, inherited optic atrophy, tobacco-alcohol amblyopia tropical atoxic neuropathy
Precautions :
none
Pregnancy and lactation :
In the recommended dosage. Belolve”” is not harmful to the fetus or breastfed child.
Side effects :
None.
Overdosage :
There is no risk of overdosage and intoxication with Belolvex”‘.
Interactions :
None.
Dosage :
In conditions where stores are presumed to be depleted (pernicious anaemia, gastrectomy): One – intramuscular injection of I ml of Belolve”” every week for 4 weeks. Thereafter I ml of Belolve”” every 3 months.
Otherwise: 1 ml of Belolve”” every 3 months.
produced by :
MINAPHARM Under Licence of
AlPHARMA Denmark
